Reaktion #760

Reaktionsgleichung

Oc1ccc(Br)cc1

C[C@@H]1CN(C(=O)OC(C

→

C[C@@H]1CN(C(=O)OC(C

Lösungsmittel

C1CCOC1

Reaktionsbedingungen

Vorschrift

A mixture of (R)-tert-butyl 3-methylpiperazine-1-carboxylate (0.025 g, 0.12 mmol), 4-bromophenol (0.043 g, 0.25 mmol), bis(tri-t- butylphosphine)palladium(0) (6.38 mg, 0.01 mmol) and [Reactants] in THF (2 mL) was flushed with nitrogen and sealed into a microwave tube. The reaction was heated to 100 °C for 20 minutes in the microwave reactor and cooled to RT. No trace of desired product by LCMS. The reaction was not progressed further.

Quelle