Reaktion #75801

Reaktionsgleichung

methanesulfonyl chloride

1-[1-(1-methoxycarbonylpiperidin-4-yl)piperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one

1-[1-(1-methoxycarbonylpiperidin-4-yl)-piperidin-4-yl]-5-methyl-1,3-dihydro-2H-benzimidazol-2-one

acetyl chloride

→

title compound

1-(1-methoxycarbonylpiperidin-4-yl)-piperidin-4-yl-5-methyl-3-(methylsulfonyl)-1,3-dihydro-2H-benzimidazol-2-one

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigewas synthesized by the method of Referential Example 5

Vorschrift

Example 12 was repeated except that the 1-[1-(1-methoxycarbonylpiperidin-4-yl)piperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one was replaced with 1-[1-(1-methoxycarbonylpiperidin-4-yl)-piperidin-4-yl]-5-methyl-1,3-dihydro-2H-benzimidazol-2-one which was synthesized by the method of Referential Example 5 and that acetyl chloride was replaced with methanesulfonyl chloride. The title compound was obtained as a colorless oil.

Quelle