Reaktion #75671

ord-f431251f81264fe1985d8880f2e0b70f

Reaktionsgleichung

Nc1cc(Cl)cc(Cl)c1
3,5-dichloroaniline
CCC(=O)C(=O)[O-]
ethylglyoxalate
C=Cc1ccc(Br)cc1
4-bromostyrene
O=C(O)C(F)(F)F
trifluoroacetic acid
CCOC(=O)C1CC(c2ccc(Br)cc2)c2c(Cl)cc(Cl)cc2N1
Compound 39
CCOC(=O)C1CC(c2ccc(Br)cc2)c2c(Cl)cc(Cl)cc2N1
4-(4-bromophenyl)-5,7-dichloro-1,2,3,4-tetrahydroquinoline-2-carboxylic Acid Ethyl Ester

Lösungsmittel

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Compound 39 was prepared by the basic process from 5.0 mmol 3,5-dichloroaniline, 5.5 mmol ethylglyoxalate solution (50% toluene), 15.0 mmol 4-bromostyrene and 5.0 mmol trifluoroacetic acid in 30.0 ml acetonitrile.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06699877B2uspto-grants-2004_03