Reaktion #75645

Reaktionsgleichung

3,5-dichloroaniline

ethylglyoxalate

2-vinylnaphthalene

trifluoroacetic acid

→

Compound 11

Ausbeute 84.0%

5,7-dichloro-4-naphthalene-2-yl-1,2,3,4-tetrahydroquinoline-2-carboxylic Acid Ethyl Ester

Ausbeute 84.0%

Lösungsmittel

acetonitrile

Reaktionsbedingungen

Vorschrift

Compound 11 was prepared in a yield of 84% by the basic process from 5.0 mmol 3,5-dichloroaniline, 5.5 mmol ethylglyoxalate solution (50% toluene), 15.0 mmol 2-vinylnaphthalene and 5.0 mmol trifluoroacetic acid in 30.0 ml acetonitrile.

Quelle