Reaktion #75552

Reaktionsgleichung

2-(2-isothiocyanatoethyl)-1-methylpyrrolidine

ammonium hydroxide

ammonium hydroxide

→

[2-(1-methylpyrrolidin-2-yl)ethyl]thiourea

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturheating

Vorschrift

The 2-(2-isothiocyanatoethyl)-1-methylpyrrolidine and concentrated ammonium hydroxide (3 mL) were heated at 100° C. for 30 minutes. Additional ammonium hydroxide (1 mL) was added and heating was continued for an additional 30 minutes. The reaction mixture was allowed to cool to room temperature and then it was lyophilized to give [2-(1-methylpyrrolidin-2-yl)ethyl]thiourea as a very viscous colorless oil.

Quelle