Reaktion #75394

ord-022556f42d9a42c2ac9750cf99436ef9

Reaktionsgleichung

CC1(C)N=CC2=C3N=C(CCc4ccccc4)N=C3C(=O)CC2C1=O
7,7-dimethyl-2-phenethyl-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione
ClCCBr
2-bromo-1-chloro-ethane
→
CC1(C)N=CC2=C3N=C(CCc4ccccc4)N=C3C(=O)C(CCCl)C2C1=O
7,7-Dimethyl-2-phenethyl-5-(2-chloro-ethyl)-5H,7H-imidazo-[4,5-h]isoquinoline-4,6-dione

Edukte

CC1(C)N=CC2=C3N=C(CCc4ccccc4)N=C3C(=O)CC2C1=O
7,7-dimethyl-2-phenethyl-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione
ClCCBr
2-bromo-1-chloro-ethane
—
crude product

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Prepared analogous to Example 23 at room temperature from 4.3 gm of 7,7-dimethyl-2-phenethyl-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione and 2.2 gm of 2-bromo-1-chloro-ethane. The viscous oily crude product was directly further processed.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04176184uspto-grants-1979_11