Reaktion #75388

ord-4f6df2d7ae0e44b3a1857c035bfd45ad

Reaktionsgleichung

CC(=O)Nc1ccc2c(c1[N+](=O)[O-])C(=O)NC(=O)C2(C)C
4,4-dimethyl-7-acetamino-8-nitro-2H,4H-isoquinoline-1,3-dione
O=C(Cl)C1CC1
cyclopropane carboxylic acid chloride
→
CC1(C)C(=O)NC(=O)c2c1ccc(NC(=O)C1CC1)c2[N+](=O)[O-]
4,4-Dimethyl-7-(cyclopropylcarbonyl-amino)-8-nitro-2H,4H-isoquinoline-1,3-dione

Edukte

CC(=O)Nc1ccc2c(c1[N+](=O)[O-])C(=O)NC(=O)C2(C)C
4,4-dimethyl-7-acetamino-8-nitro-2H,4H-isoquinoline-1,3-dione
O=C(Cl)C1CC1
cyclopropane carboxylic acid chloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Prepared analogous to Example 1b from 5.8 gm of 4,4-dimethyl-7-acetamino-8-nitro-2H,4H-isoquinoline-1,3-dione and 6.3 gm of cyclopropane carboxylic acid chloride (heating time: 30 hours).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04176184uspto-grants-1979_11