Reaktion #75383

Reaktionsgleichung

4,4-dimethyl-7-amino-8-nitro-2H,4H-isoquinoline-1,3-dione

chloroform

2,4-dimethoxybenzoylchloride

→

4,4-Dimethyl-7-(2,4-dimethoxybenzoyl amino)-8-nitro-2H,4H-isoquinoline-1,3-dione

Lösungsmittel

triethylamine

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe mixture was refluxed for 2 hours
2. 2
   TemperaturAfter cooling the solution
3. 3
   Sonstigewas evaporated
4. 4
   Filtrationthe precipitate was suction-filtered off
5. 5
   Temperaturwhile heating

Vorschrift

2.7 gm of 4,4-dimethyl-7-amino-8-nitro-2H,4H-isoquinoline-1,3-dione were admixed with 50 ml of chloroform and 2.5 ml of triethylamine. Subsequently, 2.2 gm of 2,4-dimethoxybenzoylchloride were added, and the mixture was refluxed for 2 hours. After cooling the solution was evaporated and the precipitate was suction-filtered off and digested with water while heating.

Quelle