Reaktion #75379

Reaktionsgleichung

HCl

water

p-aminophenol

4-hydroxyphthalic anhydride

→

4-(4'-Hydroxyphthalimido)phenol

Lösungsmittel

pyridine

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeIn a stirred dry flask under N2
2. 2
   Temperaturthe mixture refluxed 5 hr
3. 3
   TemperaturThis black solution was cooled
4. 4
   Filtrationfiltered
5. 5
   Waschenwashed
6. 6
   Sonstigedried
7. 7
   SonstigeRecrystallization

Vorschrift

In a stirred dry flask under N2, to a solution of 54.5 g p-aminophenol (0.5 mole) in 500 ml dry pyridine was added over 10 min at room temperature 82.0 g powdered 4-hydroxyphthalic anhydride (0.31 mole) and the mixture refluxed 5 hr. This black solution was cooled, poured into 1500 ml water, acidified with HCl, filtered, washed, and dried. M.P. 302°-304° C. Recrystallization was unnecessary. Yield 104 g, 82%.

Quelle