Reaktion #75007

Reaktionsgleichung

chlorine

phthalimide

propylene oxide

diisopropylethylamine

→

N-chlorophthalimide

Lösungsmittel

methylene chloride

Reaktionsbedingungen

Vorschrift

To 150 ml. of dry methylene chloride were added 7.35 g. (0.05 mole) of phthalimide followed by 17.5 ml. (5 equiv.) of propylene oxide and 0.065 g. (0.5 mmoles) of diisopropylethylamine. The mixture was cooled to 0° C. and saturated with chlorine. The mixture was stirred for about 24 hours to provide approximately 50% conversion to N-chlorophthalimide.

Quelle