Reaktion #74918

Reaktionsgleichung

20-Deoxynarasin sodium

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20-deoxynarasin

Ausbeute 71.8%

Lösungsmittel

ethyl acetate

dioxane

Reaktionsbedingungen

Aufarbeitung

1. 1
   WaschenThis solution was washed with 0.1 N HCl (10 ml)
2. 2
   SonstigeThe resulting organic layer was evaporated to dryness
3. 3
   Sonstigeto give a residue which

Vorschrift

20-Deoxynarasin sodium salt (200 mg) was dissolved in ethyl acetate (10 ml). This solution was washed with 0.1 N HCl (10 ml) and then twice with water (5 ml). The resulting organic layer was evaporated to dryness to give a residue which was redissolved in dioxane and lyophilized to give 139.6 mg of 20-deoxynarasin free acid as a white solid.

Quelle