Reaktion #74877

Reaktionsgleichung

1-(2-acetamidoethyl)-5-(2,4-dinitrophenylthio)tetrazole

hydrochloric acid

→

1-(2-aminoethyl)-5-(2,4-dinitrophenylthio)tetrazole hydrochloride

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONA mixture of 6.5 g
2. 2
   SonstigeThe mixture was evaporated to dryness
3. 3
   Sonstigeto give a gummy residue which
4. 4
   Sonstigecrystallized upon addition of ethanol

Vorschrift

A mixture of 6.5 g. (0.02 mol) of 1-(2-acetamidoethyl)-5-(2,4-dinitrophenylthio)tetrazole, 100 ml. of 12 N hydrochloric acid and 100 ml. of 95% ethanol was refluxed for 4.5 hours. The mixture was evaporated to dryness to give a gummy residue which crystallized upon addition of ethanol to give 1-(2-aminoethyl)-5-(2,4-dinitrophenylthio)tetrazole hydrochloride, mp 217°-219° C. (d).

Quelle