Reaktion #746398

Reaktionsgleichung

butyl-[1-(2-cyclopropyl-4,6-bis-trifluoromethyl-phenyl)-methylidene]-amine

water

Hydrochloric acid

→

2-Cyclopropyl-4,6-bis-trifluoromethyl-benzaldehyde

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe mixture was refluxed for 2 h
2. 2
   ExtraktionThe mixture was extracted three times with ethyl acetate
3. 3
   SonstigeThe combined organic phases were dried on sodium sulfate
4. 4
   Filtrationfiltered
5. 5
   Sonstigeevaporated
6. 6
   SonstigeThe crude material, brown oil (1.01 g, 34%) was used without further purification

Vorschrift

Crude butyl-[1-(2-cyclopropyl-4,6-bis-trifluoromethyl-phenyl)-methylidene]-amine (intermediate AL, 3.54 g, 10.5 mmol) was dissolved in 8 mL water. Hydrochloric acid (25%, 0.49 mL) was added and the mixture was refluxed for 2 h. The mixture was extracted three times with ethyl acetate. The combined organic phases were dried on sodium sulfate, filtered and evaporated. The crude material, brown oil (1.01 g, 34%) was used without further purification.

Quelle