Reaktion #74500

Reaktionsgleichung

3-bromo-1,8-naphthalic anhydride

compound 74

3-bromo-1,8-naphthalic anhydride

sodium hydroxide

→

3-Bromo-1-naphthoic acid

Lösungsmittel

water

water

acetic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe reaction mixture was heated
2. 2
   Temperaturat reflux for 4 days
3. 3
   FiltrationThe resulting solid was filtered
4. 4
   Sonstigedried in vacuo

Vorschrift

To a mixture of 3-bromo-1,8-naphthalic anhydride (compound 74, 22.8 g, 82.4 mmol) and sodium hydroxide (13.2 g, 330 mmol) in water (500 mL) was added a solution of mercury(II) oxide (23.2 g, 107 mmol) in water (70 mL) and glacial acetic acid (24 mL). The reaction mixture was heated at reflux for 4 days and then cooled to room temperature. The resulting solid was filtered and dried in vacuo.

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