Reaktion #74351

ord-5e2256d463de4895b857caad1e821ce5

Reaktionsgleichung

NC(=S)NC1CCCCCCC1
N-cyclooctylthiourea
COC(=O)C1(Br)CCCCC1
methyl 1-bromocyclohexanecarboxylate
→
O=C1N=C(NC2CCCCCCC2)SC12CCCCC2
2-(Cyclooctylamino)-1-thia-3-azaspiro[4.5]dec-2-en-4-one

Edukte

NC(=S)NC1CCCCCCC1
N-cyclooctylthiourea
COC(=O)C1(Br)CCCCC1
methyl 1-bromocyclohexanecarboxylate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeSynthesis

Vorschrift

Synthesis was performed from N-cyclooctylthiourea and methyl 1-bromocyclohexanecarboxylate according to Method D.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08541592B2uspto-grants-2013_09