Reaktion #74349

ord-f8208319e8294d83bb70c0bf2f4c8c7c

Reaktionsgleichung

NC(=S)NC12CC3CC(CC1C3)C2
N-tricyclo[3.3.1.0˜3,7˜]non-3-ylthiourea
COC(=O)C1(Br)CCCCC1
methyl 1-bromocyclohexanecarboxylate
→
O=C1N=C(NC23CC4CC(CC2C4)C3)SC12CCCCC2
2-(Tricyclo[3.3.1.0˜3,7˜]non-3-ylamino)-1-thia-3-azaspiro[4.5]dec-2-en-4-one

Edukte

NC(=S)NC12CC3CC(CC1C3)C2
N-tricyclo[3.3.1.0˜3,7˜]non-3-ylthiourea
COC(=O)C1(Br)CCCCC1
methyl 1-bromocyclohexanecarboxylate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeSynthesis

Vorschrift

Synthesis was performed from N-tricyclo[3.3.1.0˜3,7˜]non-3-ylthiourea and methyl 1-bromocyclohexanecarboxylate according to Method D.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08541592B2uspto-grants-2013_09