Reaktion #74348

ord-1e7764203ffd43cdb2825bbc1746b206

Reaktionsgleichung

NC(=S)NC1CC2CCC1C2
N-bicyclo[2.2.1]hept-2-ylthiourea
COC(=O)C1(Br)CCCCC1
methyl 1-bromocyclohexanecarboxylate
→
O=C1N=C(NC2CC3CCC2C3)SC12CCCCC2
2-(Bicyclo[2.2.1]hept-2-ylamino)-1-thia-3-azaspiro[4.5]dec-2-en-4-one

Edukte

NC(=S)NC1CC2CCC1C2
N-bicyclo[2.2.1]hept-2-ylthiourea
COC(=O)C1(Br)CCCCC1
methyl 1-bromocyclohexanecarboxylate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeSynthesis

Vorschrift

Synthesis was performed from N-bicyclo[2.2.1]hept-2-ylthiourea and methyl 1-bromocyclohexanecarboxylate according to Method D.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08541592B2uspto-grants-2013_09