Reaktion #74326

ord-51a9c83952c64a8fb7ae6690f3176762

Reaktionsgleichung

Cc1ccccc1NC(N)=S
N-(2-methylphenyl)thiourea
CCOC(=O)C1(Br)CCC1
ethyl 1-bromocyclobutanecarboxylate
→
Cc1ccccc1NC1=NC(=O)C2(CCC2)S1
6-[(2-Methylphenyl)amino]-5-thia-7-azaspiro[3.4]oct-6-en-8-one

Edukte

Cc1ccccc1NC(N)=S
N-(2-methylphenyl)thiourea
CCOC(=O)C1(Br)CCC1
ethyl 1-bromocyclobutanecarboxylate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeSynthesis

Vorschrift

Synthesis was performed from N-(2-methylphenyl)thiourea and ethyl 1-bromocyclobutanecarboxylate according to Method D.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08541592B2uspto-grants-2013_09