Reaktion #74320

ord-9caf7929b6af417c8f77091b32f10910

Reaktionsgleichung

NC(=S)NC12CC3CC(CC1C3)C2
N-tricyclo[3.3.1.0˜3,7˜]non-3-ylthiourea
CCOC(=O)C1(Br)CCC1
ethyl 1-bromocyclobutanecarboxylate
→
O=C1N=C(NC23CC4CC(CC2C4)C3)SC12CCC2
6-(tricyclo[3.3.1.0˜3,7˜]non-3-ylamino)-5-thia-7-azaspiro[3.4]oct-6-en-8-one

Edukte

NC(=S)NC12CC3CC(CC1C3)C2
N-tricyclo[3.3.1.0˜3,7˜]non-3-ylthiourea
CCOC(=O)C1(Br)CCC1
ethyl 1-bromocyclobutanecarboxylate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeSynthesis

Vorschrift

Synthesis was performed from N-tricyclo[3.3.1.0˜3,7˜]non-3-ylthiourea and ethyl 1-bromocyclobutanecarboxylate according to Method D.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08541592B2uspto-grants-2013_09