Reaktion #74318

ord-f482ad19203b4c638b6ae2fa0dd57a1d

Reaktionsgleichung

NC(=S)NC1CC2CCC1C2
N-bicyclo[2.2.1]hept-2-ylthiourea
CCOC(=O)C(C)(C)Br
Ethyl 2-bromoisobutyrate
→
CC1(C)SC(NC2CC3CCC2C3)=NC1=O
2-(bicyclo[2.2.1]hept-2-ylamino)-5,5-dimethyl-1,3-thiazol-4(5H)-one

Edukte

NC(=S)NC1CC2CCC1C2
N-bicyclo[2.2.1]hept-2-ylthiourea
CCOC(=O)C(C)(C)Br
Ethyl 2-bromoisobutyrate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeSynthesis

Vorschrift

Synthesis was performed from N-bicyclo[2.2.1]hept-2-ylthiourea and Ethyl 2-bromoisobutyrate according to Method C.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08541592B2uspto-grants-2013_09