Reaktion #743048

Reaktionsgleichung

N-(4-Pyrazol-1-yl-phenyl)-hydrazinecarboxylic acid tert-butyl ester

Dioxane

HCl

→

title compound

(4-Pyrazol-1-yl-phenyl)-hydrazine hydrochloride

Lösungsmittel

DCM

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigewas then removed in vacuo

Vorschrift

Title compound 51A, N-(4-Pyrazol-1-yl-phenyl)-hydrazinecarboxylic acid tert-butyl ester (0.42 g, 1.0 eq, 1.53 mmol) was suspended in a mixture of 4M HCl in Dioxane (6.5 ml, 17.0 eq, 26 mmol) and DCM (5 ml). The mixture was then stirred at room temperature for 24 hours solvent was then removed in vacuo to yield impure title compound. (0.31 g). LCMS: [M+H]+=158/175, 65% purity.

Quelle