Reaktion #74236

ord-ca533abd2c114f1db02b85f67305f175

Reaktionsgleichung

CCc1ccc(CNc2ccc3nc[nH]c3c2)cc1
N-(4-ethylbenzyl)benzimidazol-5-amine
CSc1ccc(CBr)cc1
4-methylthiobenzylbromide
O=C([O-])[O-].[K+].[K+]
K2CO3
→
CCc1ccc(CN(Cc2ccc(SC)cc2)c2ccc3[nH]cnc3c2)cc1
N-(4-(Methylthio)benzyl)-N-(4-ethylbenzyl)-1H-benzo[d]imidazol-5-amine

Edukte

CCc1ccc(CNc2ccc3nc[nH]c3c2)cc1
N-(4-ethylbenzyl)benzimidazol-5-amine
CSc1ccc(CBr)cc1
4-methylthiobenzylbromide
O=C([O-])[O-].[K+].[K+]
K2CO3

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThe compound was synthesized

Vorschrift

The compound was synthesized starting from N-(4-ethylbenzyl)benzimidazol-5-amine (251 mg; 1 mmol; 1 eq.), 4-methylthiobenzylbromide (239 mg; 1.1 mmol; 1.1 eq.) and K2CO3 (152 mg; 1.1 mmol; 1.1 eq.) according to method 6; Yield: 0.166 g (42.9%); MS m/z: 388.4

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08541596B2uspto-grants-2013_09