Reaktion #742252

Reaktionsgleichung

3-(2-hydroxy-phenyl)-acrylic acid ethyl ester

dec-9-en-1-ol

→

colourless crystals

Ausbeute 21.5%

(E)-3-(2-Hydroxy-phenyl)-acrylic acid dec-9-enyl ester

Ausbeute 21.5%

Lösungsmittel

ether

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeremoving the ethanol
2. 2
   Sonstigeformed
3. 3
   Temperaturthe reaction mixture was cooled
4. 4
   Waschenwashed with brine
5. 5
   SonstigeThe organic phase was dried
6. 6
   Sonstigeevaporated to dryness
7. 7
   workup.DISTILLATIONThe resulting oil was Kugelrohr-distilled
8. 8
   Sonstigecrystallized
9. 9
   Sonstigerecrystallized

Vorschrift

A mixture of 5.0 g 3-(2-hydroxy-phenyl)-acrylic acid ethyl ester, 6.1 g dec-9-en-1-ol and 1.0 g tetraisopropyl-ortho-titanate was heated to 150° C. removing the ethanol formed. After stirring for 2.5 hours at this temperature, the reaction mixture was cooled, diluted with ether and washed with brine. The organic phase was dried and evaporated to dryness. The resulting oil was Kugelrohr-distilled, crystallized and recrystallized to yield 1.69 g of colourless crystals.

Quelle