Reaktion #742248

Reaktionsgleichung

(E)-3-(2-hydroxy-phenyl)-2-methyl-acrylic acid

citronellol

p-toluene-sulfonic acid

water

→

colourless oil

(E)-3-(2-Hydroxy-phenyl)-2-methyl-acrylic acid 3,7 dimethyl-oct-6-enyl ester

Lösungsmittel

cyclohexane

hexane

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThen the reaction mixture was cooled down
2. 2
   Waschenwashed
3. 3
   SonstigeThe organic phase was dried
4. 4
   Filtrationfiltered
5. 5
   Sonstigeevaporated to dryness
6. 6
   SonstigeThe resulting yellow oil was purified by chromatography

Vorschrift

A solution of 6 0 g of (E)-3-(2-hydroxy-phenyl)-2-methyl-acrylic acid, 5.3 g of citronellol and 1 g of p-toluene-sulfonic acid in 150 ml of cyclohexane was refluxed for 6.5 hours using a water separator. Then the reaction mixture was cooled down, diluted with hexane and washed to neutrality with saturated sodium bicarbonate and water. The organic phase was dried, filtered and evaporated to dryness. The resulting yellow oil was purified by chromatography to yield 6.45 g of a colourless oil.

Quelle