Reaktion #736492

Reaktionsgleichung

2-chloro-3,4-dihydro-2-(2-hydroxy-5-methoxyphenyl)-4-methyl-3-oxo-2H-1,4-benzothiazine

methanol

→

titled compound

Ausbeute 85.3%

3,4-Dihydro-2-(2-hydroxy-5-methoxyphenyl)-2-methoxy-4-methyl-3-oxo-2H-1,4-benzothiazine

Ausbeute 85.3%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Filtrationthe separated crystals are collected by filtration

Vorschrift

A mixture of 2-chloro-3,4-dihydro-2-(2-hydroxy-5-methoxyphenyl)-4-methyl-3-oxo-2H-1,4-benzothiazine (14.0 g, compound No. 3) and methanol (200 ml) is stirred for 2 hours at room temperature, and the separated crystals are collected by filtration to give 11.8 g (85.3%) of the titled compound.

Quelle