Reaktion #73619

Reaktionsgleichung

4-chlorobenzoyl chloride

2-amino-4-methylthiazole-5-carboxylic acid benzylamide

→

title compound

Ausbeute 23.0%

2-(4-Chlorobenzoylamino)-4-methylthiazole-5-carboxylic Acid Benzylamide

Ausbeute 23.0%

Reaktionsbedingungen

Vorschrift

Following the procedure as described in Example 2, making variations only as required to use 4-chlorobenzoyl chloride in place of benzoyl chloride to react with 2-amino-4-methylthiazole-5-carboxylic acid benzylamide, the title compound was obtained as a white solid in 23% yield; 1H NMR (CDCl3, 300 MHz) δ 7.84 (d, J=8.5 Hz, 2H), 7.45 (d, J=8.5 Hz, 2H), 7.32-7.24 (m, 5H), 6.02 (s, 1H), 5.27 (s, 2H), 2.01 (s, 3H); MS (ES+) m/z 386.1 (M+1).

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