Reaktion #736185

Reaktionsgleichung

7-methylbenzo[b]thiophene

N-bromosuccinimide

→

7-Bromomethylbenzo[b]thiophene

Lösungsmittel

carbon tetrachloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe resulting mixture is cooled
2. 2
   Filtrationfiltered
3. 3
   Einengenconcentrated by evaporation
4. 4
   SonstigeM.p. when isolated=57° (isopropanol)

Vorschrift

7 g of 7-methylbenzo[b]thiophene, 8,5 g of N-bromosuccinimide and a spatula tip of α,α'-azoisobutyronitrile are refluxed together for 6 hours in 50 ml of carbon tetrachloride. The resulting mixture is cooled, filtered and concentrated by evaporation. The resulting raw title compound can be directly employed in the next step. M.p. when isolated=57° (isopropanol)

Quelle