Reaktion #73617

Reaktionsgleichung

4-fluorobenzoyl chloride

2-amino-4-methylthiazole-5-carboxylic acid benzylamide

→

title compound

Ausbeute 30.0%

2-(4-Fluorobenzoylamino)-4-methylthiazole-5-carboxylic Acid Benzylamide

Ausbeute 30.0%

Reaktionsbedingungen

Vorschrift

Following the procedure as described in Example 2, making variations only as required to use 4-fluorobenzoyl chloride in place of benzoyl chloride to react with 2-amino-4-methylthiazole-5-carboxylic acid benzylamide, the title compound was obtained as a white solid in 30% yield; 1H NMR (CDCl3, 300 MHz) δ 7.99-7.94 (dd, J=5.1, 8.8 Hz, 2H), 7.19-7.16 (m, 7H), 5.96 (s, 1H), 4.59 (d, J=4.6 Hz, 2H), 2.56 (s, 3H); MS (ES+) m/z 370.2 (M+1).

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