Reaktion #73293

Reaktionsgleichung

trans-4-[2-(Trityloxy)ethyl]cyclohexanol

methanesulfonyl chloride

→

trans-4-[2-(Trityloxy)ethyl]cyclohexyl methanesulfonate

Lösungsmittel

chloroform

Reaktionsbedingungen

Aufarbeitung

1. 1
   Extraktionwas then extracted with ethyl acetate
2. 2
   Waschenthe organic extracts were washed with water, and saturated NaCl
3. 3
   Trocknendried (MgSO4)
4. 4
   Einengenconcentrated in vacuo

Vorschrift

trans-4-[2-(Trityloxy)ethyl]cyclohexanol (1.95 g, 0.00504 mol) was dissolved in chloroform (40.00 mL) and the mixture was cooled to 0° C. To the reaction was added TEA (0.98 mL, 0.0071 mol) and methanesulfonyl chloride (0.47 mL, 0.0060 mol) and this mixture was stirred at 0° C. for 2 hours The reaction was then extracted with ethyl acetate and the organic extracts were washed with water, and saturated NaCl, then dried (MgSO4) and concentrated in vacuo.

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