Reaktion #732822

Reaktionsgleichung

2,5,6-Trifluoro-nicotinonitrile

pyrrolidine

→

2,5-Difluoro-6-pyrrolidin-1-yl-nicotinonitrile

Ausbeute 57.0%

Reaktionsbedingungen

Vorschrift

Prepared in 57% yield from 2,5,6-Trifluoro-nicotinonitrile and pyrrolidine according to the procedure described for Example 178A. 1H NMR (DMSO-d6) δ 1.85-1.93 (m, 4H), 3.55-3.62 (m, 4H), 8.01 (dd, J=12.2, 6.8 Hz, 1H).

Quelle