Reaktion #730225

Reaktionsgleichung

6-[3-(2-Hydroxy-1-methyl-ethylcarbamoyl)phenyl]-hex-5-ynoic acid

dimethylamine hydrochloride

→

3-(5-Dimethylcarbamoyl-pent-1-ynyl)-N-(2-hydroxy-1-methyl-ethyl)benzamide

Ausbeute 96.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeto obtain 8 (0.115 g, 0.363 mmol; 96% yield)

Vorschrift

6-[3-(2-Hydroxy-1-methyl-ethylcarbamoyl)phenyl]-hex-5-ynoic acid (4)(0.109 g, 0.377 mmol) was reacted using method C with dimethylamine hydrochloride to obtain 8 (0.115 g, 0.363 mmol; 96% yield).

Quelle