Reaktion #7287

ord-77c7461546cf4e08b92e4d0aa416cd1b

Lösungsmittel

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The cis-N-phenyl-N′-(t-butyloxycarbonyl)-cyclohexane-1,2-diamine isomer from above (0.095 g, 0.33 mmol) was dissolved in CH2Cl2 (2 mL) and treated with trifluoroacetic acid (2 mL) and the mixture stirred overnight. The reaction was worked up to afford the title compound (0.069 g) as a pale yellow solid. 1H NMR (CDCl3) 1.28–1.37 (m, 5H), 1.50–1.63 (m, 6H), 3.18 (br s, 1H), 3.42–3.45 (m, 1H), 6.63–6.70 (m, 3H), 7.16 (br t, 2H, J=7.5 Hz).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07084155B2uspto-grants-2006_08