Reaktion #72636

ord-e54f57cde3e04d3b9d3389d825d65e01

Reaktionsgleichung

CNc1sc(C)c(C)c1C#N
4,5-dimethyl-2-(methylamino)thiophene-3-carbonitrile
O=C=NC(=O)c1ccccc1
benzoyl isocyanate
→
Cc1sc(N(C)C(=O)NC(=O)c2ccccc2)c(C#N)c1C
N-((3-Cyano-4,5-dimethylthiophen-2-yl)(methyl)carbamoyl)-benzamide

Edukte

CNc1sc(C)c(C)c1C#N
4,5-dimethyl-2-(methylamino)thiophene-3-carbonitrile
O=C=NC(=O)c1ccccc1
benzoyl isocyanate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Prepared as in Example 1a from 4,5-dimethyl-2-(methylamino)thiophene-3-carbonitrile (Example 22b) and benzoyl isocyanate. MS 314 (MH+).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08541421B2uspto-grants-2013_09