Reaktion #72632

ord-24d3436e14d84b008361285b8630da6f

Reaktionsgleichung

Cc1sc(NCc2ccccc2)c(C#N)c1C
2-(benzylamino)-4,5-dimethylthiophene-3-carbonitrile
O=C(N=C=S)c1ccccc1
benzoyl isothiocyanate
→
Cc1sc(N(Cc2ccccc2)C(=S)NC(=O)c2ccccc2)c(C#N)c1C
N-(Benzyl(3-cyano-4,5-dimethylthiophen-2-yl)carbamothioyl)-benzamide

Edukte

Cc1sc(NCc2ccccc2)c(C#N)c1C
2-(benzylamino)-4,5-dimethylthiophene-3-carbonitrile
O=C(N=C=S)c1ccccc1
benzoyl isothiocyanate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Prepared as in Example 1a from 2-(benzylamino)-4,5-dimethylthiophene-3-carbonitrile (Example 20b) and benzoyl isothiocyanate. MS 406 (MH+).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08541421B2uspto-grants-2013_09