Reaktion #72533

Reaktionsgleichung

trichloroacetyl chloride

pyrrole

potassium carbonate

→

title product

2,2,2-Trichloro-1-(1H-pyrrol-2-yl)ethanone

Lösungsmittel

ethyl ether

water

ethyl ether

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe phases are separated
2. 2
   Trocknenthe organic phase is dried over sodium sulphate
3. 3
   Filtrationfiltered
4. 4
   workup.ADDITIONActive carbon is added to this organic phase
5. 5
   workup.STIRRINGAfter stirring for 5 minutes
6. 6
   Filtrationthe organic phase is filtered
7. 7
   Sonstigeevaporated to dryness

Vorschrift

To a solution of trichloroacetyl chloride (160.7 mmoles) in ethyl ether (26 ml) there is added, dropwise over a period of 3 hours, a solution of pyrrole (149 mmoles) in ethyl ether (83 ml). After stirring for a further hour, a solution of potassium carbonate (94 mmoles) in water (39 ml) is added dropwise. The phases are separated and the organic phase is dried over sodium sulphate and filtered. Active carbon is added to this organic phase. After stirring for 5 minutes, the organic phase is filtered and evaporated to dryness to yield the title product.

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