Reaktion #725325

ord-f96982342c154a2281ccc80eba376379

Reaktionsgleichung

CCO/C(=N/O)C1Cc2cc(C(=O)CC)c(O)c(Cl)c2O1
5b
CCO/C(=N/O)C1Cc2cc(C(=O)CC)c(O)c(Cl)c2O1
ETHYL (E)-7-CHLORO-2,3-DIHYDRO-6-HYDROXY-5-PROPIONYLBENZOFURAN-2-CARBOXYLATE OXIME
CC(=O)OC(C)=O
acetic anhydride
→
CCO/C(=N/OC(C)=O)C1Cc2cc(C(=O)CC)c(O)c(Cl)c2O1
white crystals
Ausbeute 89.2%
CCO/C(=N/OC(C)=O)C1Cc2cc(C(=O)CC)c(O)c(Cl)c2O1
ETHYL (E)-7-CHLORO-2,3-DIHYDRO-6-HYDROXY-5-PROPIONYL-BENZOFURAN-2-CARBOXYLATE-O-ACETYLOXIME
Ausbeute 89.2%

Edukte

CCO/C(=N/O)C1Cc2cc(C(=O)CC)c(O)c(Cl)c2O1
5b
CCO/C(=N/O)C1Cc2cc(C(=O)CC)c(O)c(Cl)c2O1
ETHYL (E)-7-CHLORO-2,3-DIHYDRO-6-HYDROXY-5-PROPIONYLBENZOFURAN-2-CARBOXYLATE OXIME
CC(=O)OC(C)=O
acetic anhydride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeEvaporation ad trituration in ethanol

Vorschrift

5b (3.45 g, 0.011 mol) was stirred in acetic anhydride overnight. Evaporation ad trituration in ethanol gave 89.2% of white crystals, M.P. 140°-142° C. Anal. (C16H18ClNO6) C,H,N.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04560558uspto-grants-1985_12