Reaktion #724468

Reaktionsgleichung

Nε-carbobenzoxy-L-lysine

ethanol

hydrogen chloride

→

desired product

Nε-Carbobenzoxy-L-lysine ethyl ester

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeEthanol was evaporated in vacuo
2. 2
   WaschenThe chloroform was washed twice with saturated aqueous sodium bicarbonate
3. 3
   Filtrationfiltered
4. 4
   Sonstigeevaporated

Vorschrift

To Nε-carbobenzoxy-L-lysine (69.7 g) was added ethanol (1000 ml) which had been saturated with anhydrous hydrogen chloride. The resulting solution was stirred at room temperature for three days. Ethanol was evaporated in vacuo and the residue was taken up in chloroform (500-600 ml). The chloroform was washed twice with saturated aqueous sodium bicarbonate, filtered and evaporated to afford the desired product as a colorless oil (69.9 g).

Quelle