Reaktion #722972

Reaktionsgleichung

dihydropyran

12-bromo-1-dodecanol

pyridinium p-toluenesulfonate

→

Tetrahydro-2-(12-bromododecanoxy)-2H pyran

Lösungsmittel

dichloromethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Waschenwashed twice with water
2. 2
   Trocknendried over anhydrous MgSO4
3. 3
   SonstigeThe dichloromethane is removed under reduced pressure
4. 4
   SonstigeIf necessary the resulting product is purified by chromatography on silica gel

Vorschrift

To a solution of 12-bromo-1-dodecanol (1 mole) in dichloromethane containing pyridinium p-toluenesulfonate (P-TSA) is added dihydropyran (2 moles). The reaction mixture is stirred for 24 hours and then washed twice with water and dried over anhydrous MgSO4. The dichloromethane is removed under reduced pressure. If necessary the resulting product is purified by chromatography on silica gel.

Quelle