Reaktion #722661

ord-df0000f5f6fc4f178a75fe6914b3b386

Reaktionsgleichung

CCCCCCCC(=O)c1ccc(CCC(CC)(COC(C)=O)NC(C)=O)cc1
2-acetamido-2-ethyl-4-(4-octanoylphenyl)butyl acetate
CCOC(=O)C(CC)C(=O)OCC
ethylmalonic acid diethyl ester
CCCCCCCC(O)c1ccc(CCC(N)(CC)CO)cc1
2-Amino-2-ethyl-4-[4-(1-hydroxyoctyl)phenyl]butanol

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstigeobtained
  2. 2
    workup.ADDITIONis treated in the same manners
  3. 3
    Sonstigeto give the subject compound

Vorschrift

In working example 77, 2-acetamido-2-ethyl-4-(4-octanoylphenyl)butyl acetate obtained by using ethylmalonic acid diethyl ester instead of propylmalonic acid diethyl ester, is treated in the same manners as working example 79 and then working example 80 to give the subject compound.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06187821B1uspto-grants-2001_02