Reaktion #722652

Reaktionsgleichung

4-(2-(2-benzyloxyphenyl)ethyl)-4-methyl-2-oxazolidinone

→

compound

Ausbeute 61.2%

4-(2-(2-Hydroxyphenyl)ethyl)-4-methyl-2-oxazolidinone

Ausbeute 61.2%

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationCatalyst was filtered off
2. 2
   Sonstigeform the reaction solution
3. 3
   workup.DISTILLATIONthe solvent was distilled away under reduced pressure
4. 4
   SonstigeThe residue was crystallized from ether-isopropyl ether

Vorschrift

To a solution of 4-(2-(2-benzyloxyphenyl)ethyl)-4-methyl-2-oxazolidinone (4.60 g) in ethanol (200 ml), 10% palladium-carbon (0.60 g) was added and the mixture was subjected to catalytic reduction at room temperature for 6 hours. Catalyst was filtered off form the reaction solution and the solvent was distilled away under reduced pressure. The residue was crystallized from ether-isopropyl ether to give the subject compound (2.0 g).

Quelle