Reaktion #720935

Reaktionsgleichung

1-(6-methoxypyrid-3-yl)ethanone

hydrobromic acid

bromine

→

2-bromo-1-(6-methoxypyrid-3-yl)ethanone hydrobromide

Lösungsmittel

acetic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeAfter precipitation
2. 2
   Filtrationwith ethyl ether and filtration, 430 mg of 2-bromo-1-(6-methoxypyrid-3-yl)ethanone hydrobromide
3. 3
   Sonstigeare obtained

Vorschrift

230 mg (1.52 mmol) of 1-(6-methoxypyrid-3-yl)ethanone, 413 μl (7.61 mmol) of hydrobromic acid, 87 μl (1.67 mmol) of bromine and 5 mL of glacial acetic acid were used in the reaction. After precipitation with ethyl ether and filtration, 430 mg of 2-bromo-1-(6-methoxypyrid-3-yl)ethanone hydrobromide are obtained, the characteristics of which are as follows:

Quelle