Reaktion #719221

ord-18866f26cb424446a33f9db994ca80d4

Reaktionsgleichung

O=C(O)c1ccc(C2CC2)c(OCC2CC2)n1
5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid
Cc1nc(C(C)(C)N)no1
α,α,5-trimethyl-1,2,4-oxadiazole-3-methanamine
→
Cc1nc(C(C)(C)NC(=O)c2ccc(C3CC3)c(OCC3CC3)n2)no1
title compound
Cc1nc(C(C)(C)NC(=O)c2ccc(C3CC3)c(OCC3CC3)n2)no1
5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid [1-methyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amide

Edukte

O=C(O)c1ccc(C2CC2)c(OCC2CC2)n1
5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid
Cc1nc(C(C)(C)N)no1
α,α,5-trimethyl-1,2,4-oxadiazole-3-methanamine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42 a) and α,α,5-trimethyl-1,2,4-oxadiazole-3-methanamine (CAN 1153831-97-0) as starting materials, MS (LC/MS): 357.1 [M+H]+.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09321727B2uspto-grants-2016_04