Reaktion #719220

ord-f61f8d81b48b438bb8fae8464605cc8b

Reaktionsgleichung

O=C(O)c1ccc(C2CC2)c(OCC2CC2)n1
5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid
CC(C)(N)c1nccs1
α,α-dimethyl-2-thiazolemethanamine
→
CC(C)(NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)c1nccs1
title compound
CC(C)(NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)c1nccs1
5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (1-methyl-1-thiazol-2-yl-ethyl)-amide

Edukte

O=C(O)c1ccc(C2CC2)c(OCC2CC2)n1
5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid
CC(C)(N)c1nccs1
α,α-dimethyl-2-thiazolemethanamine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42 a) and α,α-dimethyl-2-thiazolemethanamine (CAN 1082393-38-1) as starting materials, MS (LC/MS): 358.1 [M+H]+.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09321727B2uspto-grants-2016_04