Reaktion #719219

ord-caeca35d64934e5e914aff71233f8f28

Reaktionsgleichung

O=C(O)c1ccc(C2CC2)c(OCC2CC2)n1
5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid
CNC(=O)C(C)(C)N
2-amino-N,2-dimethyl-propanamide
→
CNC(=O)C(C)(C)NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1
title compound
CNC(=O)C(C)(C)NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1
5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (1-methyl-1-methylcarbamoyl-ethyl)-amide

Edukte

O=C(O)c1ccc(C2CC2)c(OCC2CC2)n1
5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid
CNC(=O)C(C)(C)N
2-amino-N,2-dimethyl-propanamide

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42 a) and 2-amino-N,2-dimethyl-propanamide (CAN 106914-07-2) as starting materials, MS (LC/MS): 332.2 [M+H]+.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09321727B2uspto-grants-2016_04