Reaktion #71747

Reaktionsgleichung

2-methyl-2-butene

5-methyl-4-(trifluoromethyl)-1H-imidazole-2-carbaldehyde

5-Methyl-4-(trifluoromethyl)-1H-imidazole-2-carbaldehyde

sodium chlorite

sodium dihydrogenphosphate

→

title compound

Ausbeute 118.2%

5-Methyl-4-(trifluoromethyl)-1H-imidazole-2-carboxylic acid

Ausbeute 118.2%

Reaktionsbedingungen

Vorschrift

The same operation as in Example (33c) was performed using 5-methyl-4-(trifluoromethyl)-1H-imidazole-2-carbaldehyde obtained in Example (36c) (90 mg, 0.51 mmol), sodium chlorite (95 mg, 1.05 mmol), sodium dihydrogenphosphate (154 mg, 0.99 mmol) and 2-methyl-2-butene (0.3 mL, 2.84 mmol), to obtain 117 mg of the title compound as a white solid (100%).

Quelle