Reaktion #716775

Reaktionsgleichung

solution

tert-butyl 1-(tetrahydro-2H-pyran-4-yl)piperidin-4-ylcarbamate

HCl

→

1-(tetrahydro-2H-pyran-4-yl)piperidin-4-amine

Lösungsmittel

dichloromethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONmixed vigorously at room temperature for 16 hours
2. 2
   Einengenconcentrated

Vorschrift

A solution of EXAMPLE 173A (52.57 g) in dichloromethane (900 mL) was treated with 4M HCl (462 mL), mixed vigorously at room temperature for 16 hours and concentrated.

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