Reaktion #71665

Reaktionsgleichung

2-methyl-3-pyridinecarboxylic acid

thionyl chloride

→

title compound

Ausbeute 100.0%

2-methyl-3-pyridinecarbonyl chloride

Ausbeute 100.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   EinengenThe reaction was concentrated under reduced pressure

Vorschrift

2-methyl-3-pyridinecarboxylic acid (20 g, 146 mmol) was dissolved in thionyl chloride (60 ml, 822 mmol) and stirred at room temperature for 24 h. The reaction was concentrated under reduced pressure, to obtain the title compound as a white solid (28.1 g, 146 mmol). Acyl chloride was checked by quenching a sample in MeOH, LCMS showed methyl ester derivative. {[M+H]+=152}

Quelle