Reaktion #71629

ord-bd52ff07ce2943018d46f87fab6db575

Reaktionsgleichung

N#Cc1ccc(O)cc1
4-hydroxybenzonitrile
CC(C)(C)OC(=O)N1CCC(O)CC1
1,1-dimethylethyl 4-hydroxy-1-piperidinecarboxylate
→
CC(C)(C)OC(=O)N1CCC(Oc2ccc(C#N)cc2)CC1
title compound
CC(C)(C)OC(=O)N1CCC(Oc2ccc(C#N)cc2)CC1
1,1-Dimethylethyl 4-[(4-cyanophenyl)oxy]-1-piperidinecarboxylate

Edukte

N#Cc1ccc(O)cc1
4-hydroxybenzonitrile
CC(C)(C)OC(=O)N1CCC(O)CC1
1,1-dimethylethyl 4-hydroxy-1-piperidinecarboxylate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from 4-hydroxybenzonitrile and 1,1-dimethylethyl 4-hydroxy-1-piperidinecarboxylate using a method similar to that described for D13.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08536182B2uspto-grants-2013_09