Reaktion #71480

Reaktionsgleichung

5-(2,6-dichloro-3,5-dimethoxy-phenyl)-quinoline-8-carboxylic acid

6-(4-methyl-piperazin-1-ylmethyl)-pyridin-3-ylamine

→

Title compound

5-(2,6-Dichloro-3,5-dimethoxy-phenyl)-quinoline-8-carboxylic acid [6-(4-methyl-piperazin-1-ylmethyl)-pyridin-3-yl]amide

Lösungsmittel

DCM MeOH

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe title compound was prepared in analogy to the procedure

Vorschrift

The title compound was prepared in analogy to the procedure described in Step 14.1 but using 5-(2,6-dichloro-3,5-dimethoxy-phenyl)-quinoline-8-carboxylic acid (Step 159.1), 6-(4-methyl-piperazin-1-ylmethyl)-pyridin-3-ylamine (Step 39.1), and stirring the reaction mixture for 3 h at rt. Title compound: ESI-MS: 566.0 [M+H]+; tR=3.64 min (System 1); TLC: Rf=0.24 (DCM/MeOH, 9:1).

Quelle