Reaktion #71378

ord-b801ca93d133402aa08fb63085e170a9

Reaktionsgleichung

CN(C)CCOc1ccc(N)cc1
4-(2-dimethylamino-ethoxy)-phenylamine
Cc1cccc(C)c1-c1ccc(C(=O)O)c2nccnc12
8-(2,6-dimethyl-phenyl)quinoxaline-5-carboxylic acid
→
Cc1cccc(C)c1-c1ccc(C(=O)Nc2ccc(OCCN(C)C)cc2)c2nccnc12
Title compound
Cc1cccc(C)c1-c1ccc(C(=O)Nc2ccc(OCCN(C)C)cc2)c2nccnc12
8-(2,6-Dimethyl-phenyl)-quinoxaline-5-carboxylic acid [4-(2-dimethylaminoethoxy)-phenyl]-amide

Edukte

CN(C)CCOc1ccc(N)cc1
4-(2-dimethylamino-ethoxy)-phenylamine
Cc1cccc(C)c1-c1ccc(C(=O)O)c2nccnc12
8-(2,6-dimethyl-phenyl)quinoxaline-5-carboxylic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThe title compound was prepared in analogy to the procedure

Vorschrift

The title compound was prepared in analogy to the procedure described in Step 14.1 but using 4-(2-dimethylamino-ethoxy)-phenylamine (Step 5.1) and 8-(2,6-dimethyl-phenyl)quinoxaline-5-carboxylic acid (Example 71). Title compound: ESI-MS: 441.1 [M+H]+; tR=3.52 min (System 3).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08536175B2uspto-grants-2013_09